Basophil Activation Test Discriminates Between Allergy and Tolerance in Peanut-Sensitized Children
نویسندگان
چکیده
منابع مشابه
Basophil activation test discriminates between allergy and tolerance in peanut-sensitized children
BACKGROUND Most of the peanut-sensitized children do not have clinical peanut allergy. In equivocal cases, oral food challenges (OFCs) are required. However, OFCs are laborious and not without risk; thus, a test that could accurately diagnose peanut allergy and reduce the need for OFCs is desirable. OBJECTIVE To assess the performance of basophil activation test (BAT) as a diagnostic marker f...
متن کاملAllergy or tolerance in children sensitized to peanut: prevalence and differentiation using component-resolved diagnostics.
BACKGROUND Not all peanut-sensitized children develop allergic reactions on exposure. OBJECTIVE To establish by oral food challenge the proportion of children with clinical peanut allergy among those considered peanut-sensitized by using skin prick tests and/or IgE measurement, and to investigate whether component-resolved diagnostics using microarray could differentiate peanut allergy from t...
متن کامل[Basophil activation test in the diagnosis of allergy to medicines].
In this paper we study the reliability of the basophil activation test (BAT) in the "in-vitro" diagnosis of allergy to betalactams and to metamizol, and the sensitivity and specificity of the technique are analyzed. To this end, we studied 58 patients allergic to betalactam antibiotics with a positive cutaneous test facing any derivative of penicillin and 30 healthy controls who tolerated betal...
متن کاملIs basophil activation test (BAT) really useful for allergy diagnosis?
Dear Editor, both the paper by Pereira Santos et al and the Editorial on the latest issue of this Journal, stressed on the essential, fairly irreplaceable role of basophil activation test (BAT) in allergy diagnosis (1,2). Certainly, BAT is a cell-based test and in this sense it should give fundamental insights about the role of these circulating leukocytes in hypersensitivity reactions, chronic...
متن کاملUse of a basophil activation test as a complementary diagnostic tool in the diagnosis of severe peanut allergy in adults
BACKGROUND Diagnosis of severe peanut allergy is difficult and delays in making an accurate diagnosis may place the patient at risk. Adults with a history of anaphylaxis must strictly avoid any contact with peanuts or products that may contain traces of peanuts. For these persons, conventional evaluations with skin prick testing (SPT) and IgE tests may not be sufficient to assess the risk of an...
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ژورنال
عنوان ژورنال: PEDIATRICS
سال: 2015
ISSN: 0031-4005,1098-4275
DOI: 10.1542/peds.2015-2776qq